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Who is the most famous person who has OCD? “Good Luck Chuck” star Jessica Alba is one of the tops our list. Alba says that her OCD stems from needing to control something. Her disorder does not impact her on the set. Cameron Diaz’s OCD is a bit more severe. The “Something About Mary” actress has a fear of germs and does not like to touch door nobs. Other famous actresses who have OCD are Jennifer Love Hewitt, Charlize Theron and Penelope Cruz.